库尔提斯重排反应

库尔提斯重排反应（Curtius重排反应）是一个重排反应，首先由库尔提斯（Theodor Curtius）发现，反应中酰基叠氮重排生成异氰酸酯。

关于此反应的综述参见：。

产物可与一系列亲核试剂反应：与水作用水解得到胺；与苯甲醇反应生成带有苄氧羰基保护基（Cbz）的胺类；与叔丁醇作用生成带有叔丁氧羰基保护基（Boc）的胺类，用作有机合成中的重要中间体。

羧酸1可通过与叠氮磷酸二苯酯2反应被转化为酰基叠氮3。

单词	Curtius rearrangement
释义	Curtius rearrangement 中文百科库尔提斯重排反应库尔提斯重排反应（Curtius重排反应）是一个重排反应，首先由库尔提斯（Theodor Curtius）发现，反应中酰基叠氮重排生成异氰酸酯。关于此反应的综述参见：。产物可与一系列亲核试剂反应：与水作用水解得到胺；与苯甲醇反应生成带有苄氧羰基保护基（Cbz）的胺类；与叔丁醇作用生成带有叔丁氧羰基保护基（Boc）的胺类，用作有机合成中的重要中间体。羧酸1可通过与叠氮磷酸二苯酯2反应被转化为酰基叠氮3。英语百科 Curtius rearrangement 库尔提斯重排反应 The Curtius rearrangement (or Curtius reaction or Curtius degradation), first defined by Theodor Curtius in 1885, is the thermal decomposition of an acyl azide to an isocyanate with loss of nitrogen gas. The isocyanate then undergoes attack by a variety of nucleophiles such as water, alcohols and amines, to yield a primary amine, carbamate or urea derivative respectively. Several reviews have been published.
随便看	executable documentation Executable file Executable files executable form executable image executable instruction executable machine code executable module executable module management executable path Executable program executable program notation executable program unit executable executable section executable source code executable source statement executable specification executable specification language executable state executable statement executable statement label executable symbol executable syntax notation Executable test suite

Curtius rearrangement

库尔提斯重排反应

Curtius rearrangement 库尔提斯重排反应