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单词 Curare poisoning
释义

Curare poisoning

英语百科

Curare

Strychnos toxifera by Koehler 1887

Curare /kʊˈrɑːri/ or /kjʊˈrɑːri/ is a common name for various plant extract alkaloid arrow poisons originating from Central and South America. These poisons function by competitively and reversibly inhibiting the nicotinic acetylcholine receptor (nAChR), which is a subtype of acetylcholine receptor found at the neuromuscular junction. This causes weakness of the skeletal muscles and, when administered in a sufficient dose, eventual death by asphyxiation due to paralysis of the diaphragm.

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