Aggrecan
![](/Images/godic/202412/20/Protein_ACAN_PDB_1tdq3514.png")
![](/Images/godic/202412/20/PBB_GE_ACAN_207692_s_at_tn3514.png")
![](/Images/godic/202412/20/PBB_GE_ACAN_205679_x_at_tn3514.png")
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Aggrecan, also known as cartilage-specific proteoglycan core protein (CSPCP) or chondroitin sulfate proteoglycan 1, is a protein that in humans is encoded by the ACAN gene. This gene is a member of the lectican (chondroitin sulfate proteoglycan) family. The encoded protein is an integral part of the extracellular matrix in cartilagenous tissue and it withstands compression in cartilage.