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单词 Congenital insensitivity to pain with anhidrosis
释义

Congenital insensitivity to pain with anhidrosis

原声例句
Life Noggin

One is called CIPA, or the congenital insensitivity to pain with anhidrosis.

一种称为 CIPA,或先天性无汗症。

中文百科

先天性痛觉不敏感合并无汗症

先天性痛觉不敏感合并无汗症是一遗传性感觉不敏感与自律神经性病变的罕见类型。临床表征包括无汗症、角膜溃疡,痛觉缺乏等。

其发生率为此症较易发生于同源体系的社会,但确实数字仍是未知。

遗传方面,其遗传方式为一体染色体隐性遗传,而致病基因位于第一号染色体1q21-q22的位置。

英语百科

Congenital insensitivity to pain with anhidrosis 先天性痛觉不敏感合并无汗症

Charcot joints are demonstrated in this boy with HSAN IV or congenital insensitivity to pain with anhidrosis (CIPA). The right knee and right ankle (on the left of the picture) are enlarged and distorted. The skin over the medial aspect of the ankle is darkened with a draining wound secondary to superimposed osteomyelitis. There are other areas of trauma and ulcers including a site on the right heel.

Congenital insensitivity to pain with anhidrosis (CIPA), also called hereditary sensory and autonomic neuropathy type IV—is an extremely rare inherited disorder of the nervous system which prevents the sensation of pain, heat, cold, or any real nerve-related sensations (including feeling the need to urinate); however, patients can still feel pressure. CIPA is the fourth type of hereditary sensory and autonomic neuropathy (HSAN), known as HSAN IV. (It is also referred to as HSAN Type IV). A person with CIPA cannot feel pain or differentiate even extreme temperatures. "Anhidrosis" means the body does not sweat, and "congenital" indicates that the condition is present from birth.

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