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单词 Conditioned place preference
释义

Conditioned place preference

原声例句
SciShow 合集

Their experiments involved a well-established method called conditioned place preference, where a box is divided into rooms that are different enough that mice can tell them apart.

他们的实验采用了一种行之有效的方法,称为条件性位置偏好,其中将一个盒子分成足够不同的房间,以至于老鼠可以区分它们。

英语百科

Conditioned place preference

Conditioned place preference apparatus
Different floor textures in conditioned place preference
Conditioned place preference protocol
Knockout mice are used to demonstrate behavioural or physiological differences

Conditioned place preference (CPP) is a form of Pavlovian conditioning used to measure the motivational effects of objects or experiences. This paradigm can also be used to measure conditioned place aversion with an identical procedure involving aversive stimuli instead. Both procedures usually involve mice or rats as subjects. This procedure can be used to measure extinction and reinstatement of the conditioned stimulus. Certain drugs are used in this paradigm to measure their reinforcing properties. Two different methods are used to choose the compartments to be conditioned, and these are biased vs. unbiased. The biased method allows the animal to explore the apparatus, and the compartment they least prefer is the one that the drug is administered in and the one they most prefer is the one where the vehicle is injected. This method allows the animal to choose the compartment they get the drug and vehicle in. In comparison, the unbiased method does not allow the animal to choose what compartment they get the drug and vehicle in and instead the researcher chooses the compartments.

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