After that, the coagulation cascade is activated.

之后，凝血级联反应被激活。

The coagulation cascade can get started in two ways.

凝血级联反应的启动分两种方式。

The coagulation cascade begins when one of these proteins gets proteolytically cleaved.

当这些凝血因子之一被水解裂解时，凝血级联反应就启动了。

The coagulation cascade starts when one of these proteins gets proteolytically cleaved.

当某一个凝血因子被活化即发生蛋白水解反应时，凝血级联过程就开始了。

Alright, as a quick recap - Hemophilia is a bleeding disorder that is caused by an impaired coagulation cascade.

好！快速回顾一下：血友病就是由凝血级联反应受损造成的血液疾病。

In either acute or chronic DIC, the treatment focuses on treating the underlying cause, because that's what drives the activation of the coagulation cascade.

无论是急性还是慢性的DIC，治疗方案都集中在处理原发病，因为原发病才是驱动凝血级联反应活化的元凶。

Believe it or not, this is a somewhat simplified version of the coagulation cascade; but, it contains all of the key parts needed to understand hemophilia.

总之，这就是简化版的凝血级联反应，已经包含了理解血友病病理所需的关键部分。

Signs and symptoms hemophilia A and B are nearly clinically identical, which makes sense since factors VIIIa and IXa work together in the coagulation cascade to activate factor X.

血友病A和B的体征和症状在临床上几乎相同，也说得通，因为因子VIIIa和IXa在凝血级联反应中，共同作用以激活因子X。

All right, as a quick recap, protein C and S deficiency refer to two separate hereditary hypercoagulable disorders that involve the inability to inactivate factors V and VIII in the coagulation cascade.

得！快速复习一下：蛋白C和蛋白S缺乏症是指两种独立的遗传性血液高凝功能障碍，涉及在凝血过程中无法使V因子及Ⅷ因子失活。