Clavulanic acid
(重定向自Clavulanate)


![The intermediates of the biosynthesis of Clavulanic Acid[3]](/Images/godic/202501/04/Clavualnic_Acid_Biosynthesis4017.png")
![Proposed mechanism of beta-lactam synthetase in the biosynthesis of clavulanic acid.[3]](/Images/godic/202501/04/Beta-lactam_synthetase_mechanism4017.png")
Clavulanic acid (rINN) /ˌklævjuːˈlænᵻk ˈæsᵻd/ is a β-lactam drug that functions as a mechanism-based β-lactamase inhibitor. While not effective by itself as an antibiotic, when combined with penicillin-group antibiotics, it can overcome antibiotic resistance in bacteria that secrete β-lactamase, which otherwise inactivates most penicillins.