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单词 Clavulanate
释义

Clavulanate

英语百科

Clavulanic acid

(重定向自Clavulanate)
The intermediates of the biosynthesis of Clavulanic Acid[3]
Proposed mechanism of beta-lactam synthetase in the biosynthesis of clavulanic acid.[3]

Clavulanic acid (rINN) /ˌklævjuːˈlænk ˈæsd/ is a β-lactam drug that functions as a mechanism-based β-lactamase inhibitor. While not effective by itself as an antibiotic, when combined with penicillin-group antibiotics, it can overcome antibiotic resistance in bacteria that secrete β-lactamase, which otherwise inactivates most penicillins.

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