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单词 Cheese effect
释义

Cheese effect

英语百科

Tyramine



Human biosynthesis pathway for trace amines and catecholamines[18][19]

 
 

L-Phenylalanine
L-Tyrosine
L-Dopa
Epinephrine

Phenethylamine
p-Tyramine
Dopamine
Norepinephrine

N-Methylphenethylamine
N-Methyltyramine
p-Octopamine
Synephrine
3-Methoxytyramine

AADC
AADC
AADC

PNMT
PNMT
PNMT
PNMT

AAAH
AAAH
COMT
DBH
DBH


In humans, catecholamines and phenethylaminergic trace amines are derived from the amino acid phenylalanine.

Tyramine (4-hydroxyphenethylamine; para-tyramine, mydrial or uteramin) is a naturally occurring monoamine compound and trace amine derived from the amino acid tyrosine. Tyramine acts as a catecholamine releasing agent. Notably, it is unable to cross the blood-brain barrier, resulting in only non-psychoactive peripheral sympathomimetic effects. A hypertensive crisis can result, however, from ingestion of tyramine-rich foods in conjunction with monoamine oxidase inhibitors (MAOIs).

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