布比卡因（国际非专利药品名称：bupivacaine 发音为/bjuːˈpɪvəkeɪn/）是一种氨基酰胺类的局部麻醉药。阿斯利康制药以多个商品名称进行销售，包括Marcain、Marcaine（麻卡因）、Sensorcaine及Vivacaine。

Bupivacaine, marketed under the brand name Marcaine among others, is a medication used to decrease feeling in a specific area. It is used by injecting it into the area, around a nerve that supplies the area, or into the spinal canal's epidural space. It is available mixed with a small amount of epinephrine to make it last longer. It typically begins working within 15 minutes and lasts for 2 to 8 hours. Possible side effects include sleepiness, muscle twitching, ringing in the ears, changes in vision, low blood pressure, and an irregular heart rate. There are concerns that injecting it into a joint can cause problems with the cartilage. Concentrated bupivacaine is not recommended for epidural freezing. Epidural freezing may also increase the length of labor. It is a local anaesthetic of the amide group. Bupivacaine was discovered in 1957. It is on the WHO Model List of Essential Medicines, the most important medications needed in a basic health system. Bupivacaine is available as a generic medication and is not very expensive. The wholesale cost of a vial is about 2.10 USD.