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单词 Zileuton
释义

Zileuton

英语百科

Zileuton

Abbott Laboratories stock bottle of ZYFLO (zileuton) 600 mg tablets (manufactured 1997). Also shown are ZYFLO tablets, with one tab broken. Tablets are branded with the Abbott

Zileuton (trade name ZYFLO) is an orally active inhibitor of 5-lipoxygenase, and thus inhibits leukotrienes (LTB4, LTC4, LTD4, and LTE4) formation. Zileuton is used for the maintenance treatment of asthma. Zileuton was introduced in 1996 by Abbott Laboratories and is now marketed in two formulations by Cornerstone Therapeutics Inc. under the brand names ZYFLO and ZYFLO CR. The original immediate-release formulation of zileuton, known as ZYFLO, is taken four times per day. The extended-release formulation, ZYFLO CR, is taken twice daily.

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