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单词 Verocytotoxin
释义

Verocytotoxin

英语百科

Verocytotoxin

Verocytotoxin is a Shiga-like toxin produced by the E. coli strain O157, and Shigella type 1.

It causes acute renal failure in children, as a result of Haemolytic uraemic syndrome.

The toxin has two parts. The A part damages gut epithelium through inhibiting its protein synthesis, facilitating entry to the blood stream. The 5 B parts are adapted to inserting the A part into epithelial cells.

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