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单词 Bilateral Acoustic Neurofibromatosis
释义

Bilateral Acoustic Neurofibromatosis

英语百科

Neurofibromatosis type II

(重定向自Bilateral Acoustic Neurofibromatosis)
NF-2 may be inherited in an autosomal dominant fashion, as well as through random mutation.
Schwannoma of the N. Vestibularis
Meningeomas in a patient with NFII

Neurofibromatosis Type II (or "MISME Syndrome", for "Multiple Inherited Schwannomas, Meningiomas, and Ependymomas") is an inherited disease. The main manifestation of the disease is the development of symmetric, non-malignant brain tumors in the region of the cranial nerve VIII, which is the "auditory-vestibular nerve" that transmits sensory information from the inner ear to the brain. Many people with this condition also experience visual problems. NF II is caused by mutations of the "Merlin" gene, which seems to influence the form and movement of cells. The principal treatments consist of neurosurgical removal of the tumors and surgical treatment of the eye lesions. The underlying disorder does not have any therapy due to the cell function caused by the genetic mutation.

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