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单词 Uroporphyrinogen cosynthetase
释义

Uroporphyrinogen cosynthetase

英语百科

Uroporphyrinogen III synthase

(重定向自Uroporphyrinogen cosynthetase)

Uroporphyrinogen III synthase EC4.2.1.75 is an enzyme involved in the metabolism of the cyclic tetrapyrrole compound porphyrin. It is involved in the conversion of hydroxymethyl bilane into uroporphyrinogen III. This enzyme catalyses the inversion of the final pyrrole unit (ring D) of the linear tetrapyrrole molecule, linking it to the first pyrrole unit (ring A), thereby generating a large macrocyclic structure, uroporphyrinogen III. The enzyme folds into two alpha/beta domains connected by a beta-ladder, the active site being located between the two domains.

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