Ureidopenicillin

The ureidopenicillins are a group of penicillins which are active against Pseudomonas aeruginosa.

There are three ureidopenicillins in clinical use:

They are mostly ampicillin derivatives in which the amino acid side chain has been converted to a variety of cyclic ureas. It is speculated that the added side chain mimics a longer segment of the peptidoglycan chain, more than ampicillin, and thus would bind more easily to the penicillin-binding proteins. Ureidopenicillins are not resistant to beta-lactamases.

单词	Ureidopenicillin
释义	Ureidopenicillin 英语百科 Ureidopenicillin The ureidopenicillins are a group of penicillins which are active against Pseudomonas aeruginosa. There are three ureidopenicillins in clinical use: They are mostly ampicillin derivatives in which the amino acid side chain has been converted to a variety of cyclic ureas. It is speculated that the added side chain mimics a longer segment of the peptidoglycan chain, more than ampicillin, and thus would bind more easily to the penicillin-binding proteins. Ureidopenicillins are not resistant to beta-lactamases.
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