Trempealeau National Wildlife Refuge

Trempealeau National Wildlife Refuge is a 6,226-acre (25.20 km) National Wildlife Refuge located along the Upper Mississippi River in extreme southern Buffalo County and extreme southwestern Trempealeau County in Wisconsin, USA.

It is in part a wetland, and is a significant element of the Mississippi Flyway. Consisting of backwaters away from the Mississippi and Trempealeau River. It is part of the Driftless Area, a portion of North American which remained ice free during the last ice age, creating in part the deep gorge of the Mississippi, quite visible from this refuge.