Trefentanil

Trefentanil (A-3665) is an opioid analgesic that is an analogue of fentanyl and was developed in 1992.

Trefentanil is most similar to short-acting fentanyl analogues such as alfentanil. In comparative studies, trefentanil was slightly more potent and shorter acting than alfentanil as an analgesic, but induced significantly more severe respiratory depression. For this reason trefentanil has not been adopted for clinical use, although it is still used in research.

单词	Trefentanil
释义	Trefentanil 英语百科 Trefentanil Trefentanil (A-3665) is an opioid analgesic that is an analogue of fentanyl and was developed in 1992. Trefentanil is most similar to short-acting fentanyl analogues such as alfentanil. In comparative studies, trefentanil was slightly more potent and shorter acting than alfentanil as an analgesic, but induced significantly more severe respiratory depression. For this reason trefentanil has not been adopted for clinical use, although it is still used in research.
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