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单词 Trastuzumab
释义

Trastuzumab

中文百科

曲妥珠单抗

曲妥珠单抗(通用名,国际非专利药品名称:Trastuzumab,商品名:赫赛汀(中国大陆及港澳)、贺癌平(**),罗氏Roche药厂生产)是一种作用于人类表皮生长因子受体II的单株抗体,主要用于治疗某些HER-2阳性乳癌。

英语百科

Trastuzumab 曲妥珠单抗

Trastuzumab, sold under the brandname He****tin among others, is a monoclonal antibody that interferes with the HER2/neu receptor. Its main use is to treat certain breast cancers.

The HER receptors are proteins that are embedded in the cell membrane and communicate molecular signals from outside the cell (molecules called EGFs) to inside the cell, and turn genes on and off. The HER protein, Human Epidermal Growth Factor Receptor, binds to Human Epidermal Growth Factor, and stimulates cell proliferation. In some cancers, notably certain types of breast cancer, HER2 is over-expressed, and causes cancer cells to reproduce uncontrollably.

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