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单词 Transition mutation
释义

Transition mutation

英语百科

Transition (genetics)

(重定向自Transition mutation)
Definition of transitions and transversions.

In genetics, a transition is a point mutation that changes a purine nucleotide to another purine (A ↔ G) or a pyrimidine nucleotide to another pyrimidine (C ↔ T). Approximately two out of three single nucleotide polymorphisms (SNPs) are transitions.

Transitions can be caused by oxidative deamination and tautomerization. Although there are twice as many possible transversions, transitions appear more often in genomes, possibly due to the molecular mechanisms that generate them.

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