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单词 Titanocene dichloride
释义

Titanocene dichloride

中文百科

二氯二茂钛

二氯二茂钛英语:Titanocene dichloride)是一种化学式为(η-C5H5)2TiCl2有机钛化合物,常写为Cp2TiCl2。这种茂金属是有机金属化学与有机合成中的常用试剂。其性质为亮红色固体,在空气中会缓慢的水解。Cp2TiCl2并不会形成二茂铁那样的“三明治”结构,由于其4个配体围绕一个金属中心,会形成一个四面体结构。由于其具有一定的抗肿瘤活性,已经作为化疗药物进入临床试验。

英语百科

Titanocene dichloride 二氯二茂钛

Structure of pentasulfur-titanocene complex

Titanocene dichloride is the organotitanium compound with the formula (η-C5H5)2TiCl2, commonly abbreviated as Cp2TiCl2. This metallocene is a common reagent in organometallic and organic synthesis. It exists as a bright red solid that slowly hydrolyzes in air. Cp2TiCl2 does not adopt the typical "sandwich" structure like ferrocene due to the 4 ligands around the metal centre, but rather takes on a distorted tetrahedral shape. It shows antitumour activity and was the first non-platinum complex to undergo clinical trials as a chemotherapy drug.

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