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单词 Succinate thiokinase
释义

Succinate thiokinase

英语百科

Succinyl coenzyme A synthetase

(重定向自Succinate thiokinase)
Image 2: The E. coli Succinyl-CoA Synthetase Heterotetramer; α subunits: pink and green, β subunits: yellow and blue. Pink and yellow form the one dimer and green and blue form the other dimer. PDB ID: 1CQG

Succinyl coenzyme A synthetase (SCS, also known as succinyl-CoA synthetase or succinate thiokinase or succinate-CoA ligase) is an enzyme that catalyzes the reversible reaction of succinyl-CoA to succinate. The enzyme facilitates the coupling of this reaction to the formation of a nucleoside triphosphate molecule (either GTP or ATP) from an inorganic phosphate molecule and a nucleoside diphosphate molecule (either GDP or ADP). It plays a key role as one of the catalysts involved in the citric acid cycle, a central pathway in cellular metabolism, and it is located within the mitochondrial matrix of a cell.

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