Sphingomyelin phosphodiesterase

Magnified view of SMase active site with Co2+ ions bound showing residues responsible for divalent metal cation binding. From PDB: 2dds.

A third N-SMase protein - termed nSMase3 - was recently cloned and characterized. nSMase3 bears little sequence similarity to either nSMase1 or nSMase2. However, there appears to be a high degree of evolutionary conservation from lower to higher organisms suggesting that it may comprise a unique and distinct N-SMase. The high expression of nSMase3 in heart and skeletal muscle also suggests potential roles in heart function.

单词	Sphingomyelin phosphodiesterase
释义	Sphingomyelin phosphodiesterase 英语百科 Sphingomyelin phosphodiesterase A third N-SMase protein - termed nSMase3 - was recently cloned and characterized. nSMase3 bears little sequence similarity to either nSMase1 or nSMase2. However, there appears to be a high degree of evolutionary conservation from lower to higher organisms suggesting that it may comprise a unique and distinct N-SMase. The high expression of nSMase3 in heart and skeletal muscle also suggests potential roles in heart function.
随便看	rolaidss rolamite rolamite mechanism Rolampont rolan Roland Rolanda Roland Barthes Roland circle Roland de Lassus roland de lassuss Roland Garros Roland I. Rolandian rolandic angle rolandic angle,angle of Rolando rolandic area Rolandic artery rolandic convolution Rolandic Epilepsies Rolandic epilepsy Rolandic Epilepsy,Benign Rolandic fissure Rolandic fissures Rolandic lobe