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单词 Slow reacting substance of anaphylaxis
释义

Slow reacting substance of anaphylaxis

英语百科

Slow-reacting substance of anaphylaxis

(重定向自Slow reacting substance of anaphylaxis)
LTC4
LTD4
LTE4

The Slow-reacting substance of anaphylaxis or SRS-A is a mixture of the leukotrienes LTC4, LTD4 and LTE4. Mast cells secrete it during the anaphylactic reaction, inducing inflammation. It can be found in basophils.

It induces prolonged, slow contraction of smooth muscle and has a major bronchoconstrictor role in asthma. Compared to histamine, it is approximately 5000 times more potent and has a slower onset but longer duration of action.

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