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单词 Sirbiocina
释义

Sirbiocina

英语百科

Novobiocin

Space-filling model of the novobiocin molecule
Figure 1. Biosynthesis of 3-dimethylallyl-4-hydroxybenzoic acid component of novobiocin (ring A).  Note:  Image contains multiple errors in chemical structure
Figure 2. Biosynthesis of 3-amino-4,7-dihydroxy-2H-chromen-2-one component of novobiocin (ring B)
Figure 3. Biosynthesis of L-noviose component of novobiocin (ring C)

Novobiocin, also known as albamycin or cathomycin, is an aminocoumarin antibiotic that is produced by the actinomycete Streptomyces niveus, which has recently been identified as a subjective synonym for S. spheroides a member of the order Actinobacteria . Other aminocoumarin antibiotics include clorobiocin and coumermycin A1. Novobiocin was first reported in the mid-1950s (then called streptonivicin).

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