mTOR inhibitors

Ball-and-stick model of sirolimus, the main mTOR inhibitor

Ribbon diagram of human FKBP12 in complex with rapamycin interacting with the rapamycin domain of mTOR

The four domains of mTOR at the protein level

Mammalian target of rapamycin (mTOR) is a serine/threonine kinase, which belongs to phosphatidylinositol-3 kinase (PI3K) related kinases (PIKKs) family. It regulates cellular metabolism, growth, and proliferation, and therefore is a target for the development of a number of mTOR inhibitors.

单词	Rapalog
释义	Rapalog 原声例句燎源飞轮——10月份 There is thus a search for " rapalogs" which provide the benefits of a tuned-up mtorc1 pathway without so many costs. 因此，人们正在寻找“rapalogs”，它可以提供经过调整的 mtorc1 通路的好处，而无需花费太多成本。英语百科 mTOR inhibitors Mammalian target of rapamycin (mTOR) is a serine/threonine kinase, which belongs to phosphatidylinositol-3 kinase (PI3K) related kinases (PIKKs) family. It regulates cellular metabolism, growth, and proliferation, and therefore is a target for the development of a number of mTOR inhibitors.
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Rapalog

mTOR inhibitors