Radicofani is a comune in the Province of Siena in the Italian region Tuscany, located in the natural park of Val D' Orcia about 110 kilometres (68 mi) southeast of Florence and about 60 kilometres (37 mi) southeast of Siena. As of 31 December 2012, it had a population of 1,148 and an area of 118.3 square kilometres (45.7 sq mi).