Prospidium chloride

Prospidium chloride is a spiro compound.

Definition of Prospidin: A Russian Drug, a dispiropiperazine derivative with potential cytostatic, anti-inflammatory and immune-suppressive properties. Although the exact mechanism of action of prospidin is not known, this agent was shown to interact with DNA, disrupting cell cycle at G2 phase, inhibiting phagocytic activity of monocytes and macrophages. This compound had a registration for Squamous Cell Carcinoma of the Head&Neck, reports exist about its activity in HIV-Related Kaposi Sarcoma. Prospidin has good anti-lupus activity due to its immunosuppressant effects and was also used in refractory Rheumatoid Arthritis as an anti-rheumatic drug. Usually, it has no Hematologic Toxicity. (NCI04) Prospidin is from the group