Progerin

Progerin is a truncated version of lamin A protein involved in Hutchinson-Gilford progeria syndrome. Progerin is most often generated by a silent point mutation (C1824T) in the lamin A gene, LMNA. This mutation activates a cryptic splice site and gives rise to a form of lamin A with a deletion of 50 amino acids near the C-terminus. Approximately 80% of Hutchinson-Gilford progeria syndrome cases are heterozygous for this silent point mutation within exon 11 of the LMNA gene.

单词	Progerin
释义	Progerin 英语百科 Progerin Progerin is a truncated version of lamin A protein involved in Hutchinson-Gilford progeria syndrome. Progerin is most often generated by a silent point mutation (C1824T) in the lamin A gene, LMNA. This mutation activates a cryptic splice site and gives rise to a form of lamin A with a deletion of 50 amino acids near the C-terminus. Approximately 80% of Hutchinson-Gilford progeria syndrome cases are heterozygous for this silent point mutation within exon 11 of the LMNA gene.
随便看	turnip maggot turnip meth Turnip mild mosaic virus Turnip mild yellow virus turnip moosaic virus gardner and kendrick Turnip mosaic potyvirus Turnip mosaic virus Turnip moth Turnip plant turnip plants turnip presserved with sugar and chilli turnippy turnip radich turnip radish turnip radish,shredded and dried turnip,red heart turnip root and leaf turniprooted celery turnip rooted celery turniprooted parsley Turnip rosette sobemovirus Turnip rosette virus turnips turnip,salted turnip sawflies