Other research suggests that minimal change disease and FSGS have different mechanisms of podocyte injury.

而另一些研究表明微小病变性肾病和FSGS涉及的足细胞损伤机制有所不同。

These damaged podocytes allow some plasma proteins and lipids to sneak by, which then go on to get into the urine.

这些受损的足细胞允许一些血浆蛋白和脂肪通过，进入尿液。

The epithelium of the nephron is made of specialized cells called podocytes which wrap around the basement membrane like the tentacles of an octopus.

肾单位的内皮细胞由特殊的细胞组成，称为足细胞；足细胞足突像章鱼触手一样包裹着基底膜。

Some research suggests that these changes in FSGS are a continuation from another nephrotic syndrome called minimal change disease which is also characterized by podocyte injury.

一些研究表明FSGS的病变是由另一种肾病综合征微小病变性肾病发展而来的；该病也是由足细胞损伤介导的。

Alright so on histology, there'll be segmental sclerosis and hyalinosis of the glomeruli, and under electron microscope, there's effacement of the foot processes of the podocytes.

在组织学上，患者的组织活检会出现肾小球节段性硬化和玻璃样变，在电镜下可见足细胞足突消失。

What is known, though, is that the podocytes, which are the cells that have these long tentacle-like projections, called foot processes, that wrap around the capillaries in the glomeruli, are damaged.

但我们已经知道，是有着长长的、触手样足突的、包绕肾小球毛细血管簇的足细胞受损。

Whether they bind directly to the GBM, or come from somewhere else, these immune complexes are called subepithelial deposits because they're sandwiched right between the epithelial cells or podocytes, and the GBM.

无论是直接与肾小球基膜结合或从别处而来，这些免疫复合物称之为上皮下沉积物，因为它们位于足细胞这类上皮细胞和肾小球基膜之间。