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单词 Plantazolicin
释义

Plantazolicin

英语百科

Plantazolicin

The biosynthesis of plantazolicin (PZN) entails modification of a precursor peptide by several enzymes.

Plantazolicin (PZN) is a natural antibiotic produced by the gram-positive soil bacterium Bacillus amyloliquefaciens FZB42. PZN has specifically been identified as a selective bactericidal agent active against Bacillus anthracis, the causative agent of anthrax. This natural product is a ribosomally synthesized and post-translationally modified peptide (RiPP); it can be classified further as a thiazole/oxazole-modified microcin (TOMM) or a linear azole-containing peptide (LAP).

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