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单词 Phenyltropanes
释义

Phenyltropanes

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Phenyltropane

Troparil: A structural analog of cocaine with omitted -COO- linkage – a parent compound of many MAT ligands (here in an unfavourable conformation of the O-Me. The methyl has to be at the other O, and trans)
"Phenyltropanes" (in the plural) redirects here. For an enumeration of their multiple types see list of phenyltropanes.

Phenyltropanes (PTs) were originally developed to reduce cocaine addiction and dependency. In general these compounds act as inhibitors of the plasmalemmal monoamine reuptake transporters. Although RTI holds a strong position in this field, they are not the only researchers that have prepared these analogues. This research has spanned beyond the last couple decades, and has picked up its pace in recent times, creating numerous phenyltropanes as research into cocaine analogues garners interest to treat addiction.

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