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单词 Periodic acid oxidation
释义

Periodic acid oxidation

中文百科

戴斯-马丁氧化剂 Dess–Martin periodinane

(重定向自Periodic acid oxidation)

戴斯-马丁氧化反应(Dess-Martin Oxidation)是现代有机合成中常用的氧化反应。

英语百科

Dess–Martin periodinane 戴斯-马丁氧化剂

(重定向自Periodic acid oxidation)

Dess–Martin periodinane (DMP) is a chemical reagent used to oxidize primary alcohols to aldehydes and secondary alcohols to ketones. This periodinane has several advantages over chromium- and DMSO-based oxidants that include milder conditions (room temperature, neutral pH), shorter reaction times, higher yields, simplified workups, high chemoselectivity, tolerance of sensitive functional groups, and a long shelf life. It is named after the American chemists Daniel Benjamin Dess and James Cullen Martin who developed the reagent in 1983. It is based on IBX, but due to the acetate groups attached to the central iodine atom, DMP is much more reactive than IBX and is much more soluble in organic solvents.

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