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单词 Peptidase P
释义

Peptidase P

英语百科

Angiotensin-converting enzyme

proposed ACE catalytic mechanism
Schematic diagram of the renin–angiotensin–aldosterone system

Angiotensin-converting enzyme (EC3.4.15.1), or "ACE" is a central component of the renin-angiotensin system (RAS)), which controls blood pressure by regulating the volume of fluids in the body. It converts the hormone angiotensin I to the active vasoconstrictor angiotensin II. Therefore, ACE indirectly increases blood pressure by causing blood vessels to constrict. ACE inhibitors are widely used as pharmaceutical drugs for treatment of cardiovascular diseases.

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