CYP17A1

（重定向自P450C17）

17α-hydroxylase converts pregnenolone and progesterone to their 17-hydroxy forms, and converts 17-hydroxypregnenolone and 17-hydroxyprogesterone to DHEA and androstenedione, respectively. It corresponds to the downward arrows in this reaction scheme.

Steroidogenesis, showing, at left side, both reactions of 17-alpha hydroxylase, and both actions of 17, 20 lyase.

Cytochrome P450 17A1, or steroid 17-alpha-monooxygenase, or 17α-hydroxylase/17,20 lyase/17,20 desmolase is an enzyme that in humans is encoded by the CYP17A1 gene. It is found in the zona reticularis of the adrenal cortex and zona fasciculata as well as gonadal tissues. This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are generally regarded as monooxygenases that catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids, and other lipids, including the remarkable carbon-carbon bond scission catalyzed by this enzyme. This protein localizes to the endoplasmic reticulum. It has both 17alpha-hydroxylase and 17,20-lyase activities, and is a key enzyme in the steroidogenic pathway that produces progestins, mineralocorticoids, glucocorticoids, androgens, and estrogens.

单词	P450C17
释义	P450C17 英语例句库 In the PC world, archiving and compression usually happen together by using utilities such as PKZIP. 在PC机世界中，归档文件和压缩文件通常使用PKZIP应用程序来压缩。 Only the first page of the PC Research multipage file will be shown. 仅仅计算机调查多页文件中的第一页会展示. The session is done with you and your preclear (pc) seated across from each other. 你和你的待清新者对面而坐来完成听析。 With these extras your PC will become the all singing, all dancing box the salesman claimed it would be. 有了这些外加设备，你的电脑就成了推销员口中的技术先进，功能齐全的盒子了。 Introduces the application of PC programmable controller at uniflow high-speed elevator, and the principle of controlling uniflow high-speed elevator. 介绍PC可编程控制器及其在直流高速电梯上的应用,及直流高速电梯的控制原理。 Altough I didn’t know the difference between a Mac and PC, once Macs were so beige, palid and ordinary as any lowsy PC. 比如微软和苹果，都有它们各自的指导手册，详细规定了颜色，透视及其他细节。 To deal with such problems, a phase congruency(PC) based on target tracking method is proposed, which adopts log Gabor to get multi-directional PC images. 针对这些问题，介绍了基于相位一致性检测的目标跟踪算法。 Unchain your mobile PC. 突破移动PC的限制。 PC is used to store and process the displacement data and faradic voltage data which are acquired by multi-function data-collecting card in the meantime. 通过多功能数据采集卡同时获得位移数据以及感应电压数据，用PC机实现数据的存储处理。 BSI is a manufacturer of high-end PC systems in portable, and industrial rackmount computer system designs for use in business, research, engineering and industrial settings. BSI是一个高端的便携式和工业机架式计算机系统的生产商，设计的电脑系统在商业，科研，工程和工业等行业中都有运用。原声例句 CNN 10 学生英语 2018年11月合集 PC bangs or PC gaming rooms to you and I sprung up all over Seoul. 电脑房和网吧如雨后春笋般的出现在首尔各个地方。乔布斯如何改变世界 Hello, I'm a Mac. Hello, I'm a PC. 你好，我是Mac。你好，我是PC（windows）。《卫报》（文章版） His parents let him buy a PC that he put together himself. 他的父母让他买了一台他自己组装的电脑。 America The Story of Us There are just 300,000 PCs in 1980. 1980年只有30万台个人电脑。杜克大学公开课：库克访谈 You're working for the top PC company in the world. 你正在为全世界顶尖的PC公司工作。 BEC高级听力真题（第1辑） Jim O'Brien heads the UK division of American PC company Hacker. 吉姆·奥布莱恩是美国电脑公司骇客英国分部的负责人。历年英语专业八级真题听力（专项） Then a few years later, I bought a PC and I learnt how to do word processing, too. 几年后，我买了一台电脑，也学会了文字处理。《卫报》（文章版） By moving a programme from his own PC on to the KPN computer, Edwin could bypass the wall. 通过将一个程序从他自己的电脑移到KPN的电脑上，埃德温就可以绕过这堵墙。 TED演讲（视频版）双语精选 And today, data centers, they use blade servers, which is PC technology. 如今，数据中心都在使用刀锋服务器，这是个人电脑用的技术。乔布斯如何改变世界 Turns out people don't want to 10 grand for a PC. 事实证明大家不愿意花一万块买个人电脑。经济学人（汇总） In 2018 Epic launched a PC games store, charging a 12% commission. 2018年，Epic推出了一款电脑端游戏商店，收取12%的佣金。美语情景对话 I think if I have a PC then I would also forget my phone. 我想如果我有电脑的话，我也会忘了手机的。潮流科技大事件！ It's two times faster than the best-selling PC, and it's just 329 bucks. 它比卖的最好的电脑运行速度的二倍还快。仅仅只有329美元。潮流科技大事件！ And Cortana will launch on your phone or your PC, and the give you answers. 你手机或电脑上的 Cortana 就会启动并回答你。财富精英励志演讲 I'll have more to say about that later, when I talk about our PC strategy. 稍后等我谈到我们的PC战略时将对此详细论述。 TED演讲（音频版） 2014年4月合集 The poor PC guy. They're duct taping his head. They're just wrapping it on him. 这个可怜的PC男孩, 头上带着管子, 他们给他包装成那样儿. 美语情景对话 OK. Do you have a laptop or a PC? 你有笔记本电脑或者个人电脑吗？ BEC高级听力真题（第5辑） The number of desktop PCs, too, was reduced significantly. 台式电脑的数量也大幅减少。世界名人简介 He is the best-known entrepreneur of the PC revolution. 在个人电脑的革命史中，他也是最知名的企业家。历届苹果发布会 The iPod mini runs on Mac or PC, $249. iPod mini可以在Mac或者PC上运行，售价为249美元。英语百科 CYP17A1 （重定向自P450C17） Cytochrome P450 17A1, or steroid 17-alpha-monooxygenase, or 17α-hydroxylase/17,20 lyase/17,20 desmolase is an enzyme that in humans is encoded by the CYP17A1 gene. It is found in the zona reticularis of the adrenal cortex and zona fasciculata as well as gonadal tissues. This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are generally regarded as monooxygenases that catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids, and other lipids, including the remarkable carbon-carbon bond scission catalyzed by this enzyme. This protein localizes to the endoplasmic reticulum. It has both 17alpha-hydroxylase and 17,20-lyase activities, and is a key enzyme in the steroidogenic pathway that produces progestins, mineralocorticoids, glucocorticoids, androgens, and estrogens.
随便看	afterservice after service export after servise after session undertone Afterset after settler after sexual intercourse test aftershaft aftershaft, afterfeather aftershave after shave lotion aftershave lotion after shave powder after sheer after shipment aftershock After Shock aftershock sequence aftershock wave aftershoot after shoulder velox wave system Aftershow aftershows aftershrinkage after shrinkage