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单词 P2X Receptor
释义

P2X Receptor

中文百科

P2X受体 P2X purinoreceptor

(重定向自P2X Receptor)

P2X受体英语:P2X receptors,或称为P2X嘌呤受体 英语:P2X purinoreceptor)是一个阳离子渗透型配体门控离子信道家族,能同细胞外的ATP结合,属于一个更大的嘌呤受体家族。P2X受体存在于一系列动物中,包括人、鼠类、兔、鸡、斑马鱼、牛蛙、吸虫甚至是变形虫。

英语百科

P2X purinoreceptor P2X受体

(重定向自P2X Receptor)
Figure 1. Schematic representation showing the membrane topology of a typical P2X receptor subunit. First and second transmembrane domains are labeled TM1 and TM2.
Figure 2. Crystal structure of the zebrafish P2X4 receptor (deltaP2X4-B) channel as viewed from the side (left), extracellular (top right), and intracellular (bottom right) perspectives(PDB: 3I5D​)

P2X receptors are a family of cation-permeable ligand gated ion channels that open in response to the binding of extracellular adenosine 5'-triphosphate (ATP). They belong to a larger family of receptors known as the purinergic receptors. P2X receptors are present in a diverse array of organisms including humans, mouse, rat, rabbit, chicken, zebrafish, bullfrog, fluke, and amoeba.

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