Phenylpropanolamine
![RS-Norephedrin](/Images/godic/202501/31/Phenylpropanolamine.svg2758.png")
![Ball-and-stick model of the phenylpropanolamine molecule](/Images/godic/202501/31/Phenylpropanolamine_molecule_ball2758.png")
![Metabolic pathways of amphetamine in humans
4-Hydroxyphenylacetone
Phenylacetone
Benzoic acid
Hippuric acid
Amphetamine
Norephedrine
4-Hydroxyamphetamine
4-Hydroxynorephedrine
Para-Hydroxylation
Para-Hydroxylation
Para-Hydroxylation
Beta-Hydroxylation
Beta-Hydroxylation
OxidativeDeamination
Oxidation
GlycineConjugation
In humans, norephedrine occurs as a metabolite of amphetamine. The beta-hydroxylation of amphetamine is mediated by dopamine β-hydroxylase.](/Images/godic/202501/31/Amph_Pathway2758.png")
![Space filling model of phenylpropanolamine](/Images/godic/202501/31/Phenylpropanolamine_spacefill2758.png")
Phenylpropanolamine (BAN and INN; PPA, β-hydroxyamphetamine), also known as the stereoisomers (−)-norephedrine and norpseudoephedrine, is a psychoactive drug of the phenethylamine and amphetamine chemical classes which is used as a stimulant, decongestant, and anorectic agent. It is commonly used in prescription and over-the-counter cough and cold preparations. In veterinary medicine, it is used to control urinary incontinence in dogs under trade names Propalin and Proin.