奥瑟姆河是保加利亚的河流，位于该国北部，河道全长314公里，流域面积2,824平方公里，河畔城镇有特罗扬、洛维奇、莱特尼察和列夫斯基。

The Òsam (Bulgarian:Осъм) is a river in northern Bulgaria. Its drainage basin is in between that of the river Vit to the west and the Yantra system to the east. The river has two main tributaries in its upper course: the Black Osam takes its source from the foot of Levski Peak in the Balkan Mountains, at an altitude of 1,821 m (5,974 ft), while the White Osam has its source on the northern slopes of the Kozya Stena peak. In Troyan, the black and white Osam join. It runs north towards Lovech, then north-east until Letnitsa and Levski, where it turns north-west until it flows into the river Danube 5 km west of the town of Nikopol. The ancient name of the river was Assamus.