请输入您要查询的英文单词:

 

单词 Norfenfluramine
释义

Norfenfluramine

英语百科

Norfenfluramine

Ball-and-stick model of the norfenfluramine molecule

Norfenfluramine, or 3-trifluoromethylamphetamine, is a never-marketed drug of the amphetamine family which behaves as a serotonin and norepinephrine releasing agent and potent 5-HT2A, 5-HT2B, and 5-HT2C agonist. The action of norfenfluramine on 5-HT2B receptors on heart valves leads to a characteristic pattern of heart failure following proliferation of cardiac fibroblasts on the tricuspid valve, known as cardiac fibrosis. This side effect led to the withdrawal of fenfluramine as an anorectic agent worldwide, and to the withdrawal of benfluorex in Europe, as both fenfluramine and benfluorex form norfenfluramine as an active metabolite. It is a human TAAR1 agonist.

随便看

 

英汉双解词典包含3607232条英汉词条,基本涵盖了全部常用单词的翻译及用法,是英语学习的有利工具。

 

Copyright © 2004-2022 Newdu.com All Rights Reserved
京ICP备09058993号 更新时间:2025/8/10 19:32:22