Short linear motif

The Human papilloma virus E7 oncoprotein mimic of the LxCxE motif (red) bound to the host Retinoblastoma protein (dark grey)(PDB: 1gux)

MDM2 SWIB domain-binding motif mimic drug Nutlin bound to MDM2(PDB: 3lbk)

In molecular biology Short Linear Motifs (also known as SLiMs, Linear Motifs or minimotifs) are short stretches of protein sequence that mediate protein protein interaction.

The first definition was given by Tim Hunt:

单词	Minimotif
释义	Minimotif 英语百科 Short linear motif In molecular biology Short Linear Motifs (also known as SLiMs, Linear Motifs or minimotifs) are short stretches of protein sequence that mediate protein protein interaction. The first definition was given by Tim Hunt:
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Minimotif

Short linear motif