Second, cortisol starts cross-reacting with mineralocorticoid receptors, which normally only binds a related steroid hormone - mineralocorticoids which are secreted from the zona glomerulosa layer of the adrenal cortex.

第二，皮质醇对盐皮质激素受体产生交叉反应；此类受体一般只与一种相关的类固醇激素结合，即从肾上腺皮质的球状带层分泌的盐皮质激素。