Metofoline
![](/Images/godic/202501/27/Methopholine.svg5050.png")
![4'-Nitromethopholine](/Images/godic/202501/27/4-nitromethopholine_structure5050.png")
Methopholine is an opioid analgesic drug discovered in the 1950s by a team of Swiss researchers at Hoffmann-La Roche.
Methopholine is an isoquinoline derivative which is not structurally related to most other opioids. However, its structural similarity to papaverine is notable.