Methotrexate

The coenzyme folic acid (top) and the anti-cancer drug methotrexate (bottom) are very similar in structure. As a result, methotrexate is a competitive inhibitor of many enzymes that use folates.

Methotrexate (green) complexed into the active site of DHFR (blue)

Methotrexate (MTX), formerly known as amethopterin, is an antimetabolite and antifolate drug.

It is used in treatment of cancer, autoimmune diseases, ectopic pregnancy, and for the induction of medical abortions. It acts by inhibiting the metabolism of folic acid via dihydrofolate reductase.

单词	Ledertrexate
释义	Ledertrexate 英语百科 Methotrexate Methotrexate (MTX), formerly known as amethopterin, is an antimetabolite and antifolate drug. It is used in treatment of cancer, autoimmune diseases, ectopic pregnancy, and for the induction of medical abortions. It acts by inhibiting the metabolism of folic acid via dihydrofolate reductase.
随便看	inhospitably in hospital inhospital inhospitalious inhospitalities inhospitality Inhospital Mortalities In Hospital Mortalities Inhospital Mortality In Hospital Mortality in hospital mortality rate in hot blood in hot haste in hot pursuit in hot water inhour Inhour equation inhour formula inhour unit inhouse In house in house adv inhouse compounding in house compounding in house compouter

Ledertrexate

Methotrexate