Multiple myeloma 多发性骨髓瘤
（重定向自Kahler disease）
![](/Images/godic/202501/21/Plasmacytoma_ultramini11025.jpg")
![Illustration showing the most common site of bone lesions in vertebrae](/Images/godic/202501/21/Blausen_0656_MultipleMyeloma1026.png")
![](/Images/godic/202501/21/Plasmacytoma11026.jpg")
![Age-standardized death from lymphomas and multiple myeloma per 100,000 inhabitants in 2004.[38]
no data
less than 1.8
1.8–3.6
3.6–5.4
5.4–7.2
7.2–9
9–10.8
10.8–12.6
12.6–14.4
14.4–16.2
16.2–18
18–19.8
more than 19.8](/Images/godic/202501/21/Lymphomas,_multiple_myeloma_world_map_-_Death_-_WHO2004.svg1026.png")
Multiple myeloma is a cancer of plasma cells, a type of white blood cell normally responsible for producing antibodies.
In multiple myeloma, collections of abnormal plasma cells accumulate in the bone marrow, where they interfere with the production of normal blood cells. Most cases of multiple myeloma also feature the production of a paraprotein—an abnormal antibody which can cause kidney problems. Bone lesions and hypercalcemia (high blood calcium levels) are also often encountered. Multiple myeloma is diagnosed with blood tests (serum protein electrophoresis, serum free kappa/lambda light chain assay), bone marrow examination, urine protein electrophoresis, and X-rays of commonly involved bones.