Atmospheric-pressure chemical ionization

（重定向自APCI）

Atmospheric pressure chemical ionization (APCI) is an ionization method used in mass spectrometry (commonly LC-MS) which utilizes gas-phase ion-molecule reactions at atmospheric pressure. It is an ionization method that is similar to chemical ionization (commonly used in GC-MS) where corona discharges on a solvent spray produce primary ions. APCI is mainly used with polar and relatively nonpolar compounds with a molecular weight of less than 1500 Da, generally giving monocharged ions. Because of its ability to run in sequence with HPLC, it has gained a large popularity in trace analysis detection and pharmacology.

单词	APCI
释义	APCI 英语百科 Atmospheric-pressure chemical ionization （重定向自APCI） Atmospheric pressure chemical ionization (APCI) is an ionization method used in mass spectrometry (commonly LC-MS) which utilizes gas-phase ion-molecule reactions at atmospheric pressure. It is an ionization method that is similar to chemical ionization (commonly used in GC-MS) where corona discharges on a solvent spray produce primary ions. APCI is mainly used with polar and relatively nonpolar compounds with a molecular weight of less than 1500 Da, generally giving monocharged ions. Because of its ability to run in sequence with HPLC, it has gained a large popularity in trace analysis detection and pharmacology.
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