传染性皮下及造血组织坏死症（英文：Infectious hypodermal and hematopoietic necrosis，IHHNv）是存在于海洋水生物中的一种病毒，尤其是虾种。受影响的虾类为Penaeus monodon（草虾）。严重则致死，不然则会影响虾成长的速度，或是导致畸型的虾种。此病毒也可以感染白虾（Litopenaeus vannamei）。感染的主要部位为鳃、表皮细胞、结缔组织、造血组织和淋巴组织。病毒较活跃于西半球，如墨西哥、夏威夷，和东南亚等。

Infectious hypodermal and hematopoietic necrosis (IHHN) is a viral disease of penaeid shrimp that causes mass mortality (up to 90%) among the Western blue shrimp (Penaeus stylirostris) and severe deformations in the Pacific white shrimp (P. vannamei). It occurs in Pacific farmed and wild shrimp, but not in wild shrimp on the Atlantic coast of the Americas. The shrimp-farming industry has developed several broodstocks of both P. stylirostris and P. vannamei that are resistant against IHHN infection.