Amrinone

（重定向自Inamrinone）

Amrinone (INN) or inamrinone (USAN, changed in 2000 to prevent confusion with amiodarone), trade name Inocor, is a pyridine phosphodiesterase 3 inhibitor. It is a drug that may improve the prognosis in patients with congestive heart failure. Amrinone has been shown to increase the contractions initiated in the heart by high gain calcium induced calcium release (CICR). The positive inotropic effect of amrinone is mediated by the selective enhancement of high gain CICR which contributes to the contraction of myocytes by phosphorylation through cAMP dependent protein kinase A (PKA) and Ca calmodulin kinase pathways.

单词	Inamrinone
释义	Inamrinone 英语百科 Amrinone （重定向自Inamrinone） Amrinone (INN) or inamrinone (USAN, changed in 2000 to prevent confusion with amiodarone), trade name Inocor, is a pyridine phosphodiesterase 3 inhibitor. It is a drug that may improve the prognosis in patients with congestive heart failure. Amrinone has been shown to increase the contractions initiated in the heart by high gain calcium induced calcium release (CICR). The positive inotropic effect of amrinone is mediated by the selective enhancement of high gain CICR which contributes to the contraction of myocytes by phosphorylation through cAMP dependent protein kinase A (PKA) and Ca calmodulin kinase pathways.
随便看	exit block of Wenckebach phenomenon exit block type junctional premature beat exit blower Exit bond exit boundary exit boundary point exit branch exit bridle exit button exit button relay exit capacity exit card exit casing exit certificate exit channel exit channel spin exit charge Exit code exit command exit concentration exit condition exit conditions exit cone exit control exit conveyor