X-linked hypophosphatemia

X-linked dominant inheritance works differently depending upon whether the mother (left image) or father (right image) is the carrier of a gene that causes a disease or disorder

X-linked hypophosphatemia (XLH), also called X-linked dominant hypophosphatemic rickets, X-linked vitamin d-resistant rickets , is an X-linked dominant form of rickets (or osteomalacia) that differs from most cases of rickets in that ingestion of vitamin D is relatively ineffective. It can cause bone deformity including short stature and genu varum (bow leggedness). It is associated with a mutation in the PHEX gene sequence (Xp.22) and subsequent inactivity of the PHEX protein. The prevalence of the disease is 1:20000. The leg deformity can be treated with Ilizarov frames and CHAOS surgery.

单词	Hypophosphatemic rickets
释义	Hypophosphatemic rickets 英语百科 X-linked hypophosphatemia X-linked hypophosphatemia (XLH), also called X-linked dominant hypophosphatemic rickets, X-linked vitamin d-resistant rickets , is an X-linked dominant form of rickets (or osteomalacia) that differs from most cases of rickets in that ingestion of vitamin D is relatively ineffective. It can cause bone deformity including short stature and genu varum (bow leggedness). It is associated with a mutation in the PHEX gene sequence (Xp.22) and subsequent inactivity of the PHEX protein. The prevalence of the disease is 1:20000. The leg deformity can be treated with Ilizarov frames and CHAOS surgery.
随便看	pannonit pannor pannoranic pannosa pannose pannosus Pannota pannous pannozzo Pannu pannum pannus annularis pannus carateus pannuscarnosus pannus carnosus pannus carnosus,pannus crassus pannuscorium pannus corneae pannus crassus pannus degenerativus pannus eczematosus pannus pannus hepaticus pannus pan pannus regenerativus

Hypophosphatemic rickets

X-linked hypophosphatemia