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单词 Homologous desensitization
释义

Homologous desensitization

英语百科

Homologous desensitization

Homologous desensitization occurs when a receptor decreases its response to a signalling molecule when that agonist is in high concentration. It is a process whereby after prolonged agonist exposure, the receptor is uncoupled from its signaling cascade, and thus the biological effect of receptor activation is attenuated.

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