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单词 Histocompatibility antigens class ii
释义

Histocompatibility antigens class ii

英语百科

MHC class II

(重定向自Histocompatibility antigens class ii)
Schematic representation of MHC class II.
 Pathway showing how MHC-II distribution is controlled within Immature Dendritic Cells.

MHC (major histocompatibility complex) class II molecules are a family of molecules normally found only on antigen-presenting cells such as dendritic cells, mononuclear phagocytes, some endothelial cells, thymic epithelial cells, and B cells.

The antigens presented by class II peptides are derived from extracellular proteins (not cytosolic as in class I); hence, the MHC class II-dependent pathway of antigen presentation is called the endocytic or exogenous pathway.

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