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单词 Heparin induced thrombocytopenia
释义

Heparin induced thrombocytopenia

英语百科

Heparin-induced thrombocytopenia

(重定向自Heparin induced thrombocytopenia)
Molecular structure of argatroban, a direct thrombin inhibitor used as an alternative to heparin in HIT.

Heparin-induced thrombocytopenia (HIT) is the development of thrombocytopenia (a low platelet count), due to the administration of various forms of heparin, an anticoagulant. HIT predisposes to thrombosis, the abnormal formation of blood clots inside a blood vessel, and when thrombosis is identified the condition is called heparin-induced thrombocytopenia and thrombosis (HITT). HIT is caused by the formation of abnormal antibodies that activate platelets. If someone receiving heparin develops new or worsening thrombosis, or if the platelet count falls, HIT can be confirmed with specific blood tests.

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