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单词 hemosiderinuria
释义

hemosiderinuria

英汉-汉英词典
含铁血黄素尿症
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hemosiderinuria 含铁血黄素尿
英语百科

Hemosiderinuria

Hemosiderinuria (syn. haemosiderinuria), "brown urine", occurs with chronic intravascular hemolysis, in which hemoglobin is released from RBCs into the bloodstream in excess of the binding capacity of haptoglobin. The excess hemoglobin is filtered by the kidney and reabsorbed in the proximal convoluted tubule, where the iron portion is removed and stored in ferritin or hemosiderin. The tubule cells of the proximal tubule slough off with the hemosiderin and are excreted into the urine, producing a "brownish" color. It is usually seen 3-4 days after the onset of hemolytic conditions.

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